Augmentin (amoxicillin/clavulanate)
Company: SmithKline Beecham
Approval Status: Approved February 1996
Treatment for: sinusitis, bronchitis, pneumonia
Areas: Respiratory

General Information
A new adult dosing regimen of Augmentin has been approved. Augmentin is an antibiotic used to treat various respiratory-tract infections, including sinusitis, bronchitis, and pneumonia.

In the new regimen, Augmentin is administered twice a day (BID), every 12 hours, in contrast to three-times-a-day regimen used since Augmentin was introduced in the United States.

The BID regimen for more severe infections and infections of the respiratory tract consists of a new tablet containing 875 mg of amoxicillin and 125 mg of clavulanate potassium. In addition, the currently marketed tablet containing 500 mg of amoxicillin and 125 mg of clavulanate potassium can now be prescribed on a twice-a-day regimen for less severe infections that may be treated with a lower dose.

Augmentin should not be used in subjects with a history of allergic reactions to any penicillin or with a previous history of Augmentin-associated cholestatic jaundice/hepatic dysfunction.


--------------------------------------------------------------------------------

Side Effects
The side effects of Augmentin, which are primarily mild and self-limiting, include diarrhea and nausea. In adult subjects treated for more severe infections during clinical trials, there was a 60% reduction in the number of subjects experiencing severe diarrhea or withdrawing from trials because of diarrhea.

http://www.medilexicon.com/drugs/augmentin.php
DRUG DESCRIPTION
AUGMENTIN (amoxicillin/clavulanate potassium) is an oral antibacterial combination consisting of the semisynthetic antibiotic amoxicillin and the β-lactamase inhibitor, clavulanate potassium (the potassium salt of clavulanic acid). Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid. The amoxicillin molecular formula is C16H19N3O5S•3H2O, and the molecular weight is 419.46. Chemically, amoxicillin is (2S,5R,6R)-6-[(R)­ (-)-2-Amino-2-(p-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2­carboxylic acid trihydrate and may be represented structurally below as:






Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a β-lactam structurally related to the penicillins and possesses the ability to inactivate a wide variety of β-lactamases by blocking the active sites of these enzymes. Clavulanic acid is particularly active against the clinically important plasmid-mediated β-lactamases frequently responsible for transferred drug resistance to penicillins and cephalosporins. The clavulanate potassium molecular formula is C8H8KNO5, and the molecular weight is 237.25. Chemically, clavulanate potassium is potassium (Z)­ (2R,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]-heptane-2-carboxylate, and may be represented structurally below as:






Inactive Ingredients: Colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, and titanium dioxide.

Each tablet of Augmentin (amoxicillin/clavulanate potassium) contains 0.63 mEq potassium.






http://www.rxlist.com/augmentin-drug.htm

Found my favorite IXth std. poetry on the net............



O where have you been, Lord Randal, my son ?
O where have you been, my bonny young man ?
I've been with my sweetheart, mother make my bed soon
For I'm sick to the heart and I fain would lie down.

And what did she give you, Lord Randal, my son ?
And what did she give you, my bonny young man ?
Eels boiled in brew, mother make my bed soon
For I'm sick to the heart and I fain would lie down.

What's become of your bloodhounds, Lord Randal, my son ?
What's become of your bloodhounds, my bonny young man ?
O they swelled and died, mother make my bed soon
For I'm sick to the heart and I fain would lie down.

Lord Randal


O I fear you are poisoned, Lord Randal, my son,
O I fear you are poisoned, my bonny young man.
O yes, I am poisoned, mother make my bed soon
For I'm sick to the heart and I fain would lie down.

What will you leave your brother, Lord Randal, my son ?
What will you leave your brother, my bonny young man ?
My horse and the saddle, mother make my bed soon
For I'm sick to the heart and I fain would lie down.

What will you leave your sister, Lord Randal, my son ?
What will you leave your sister, my bonny young man ?
My gold box and rings, mother make my bed soon
For I'm sick to the heart and I fain would lie down.

What will you leave your true love, Lord Randal, my son ?
What will you leave your true love, my bonny young man ?
The tow and the halter to hang on yon tree,
And let her hang there for the poisoning of me.

http://mysongbook.de/msb/songs/r_clarke/lordrand.htm

Hi..
>
> When I was doing my school, in 8th standard, I had a poem as a quote
> from memory describing about a girl who travels in a subway train, her
> thoughts were wandering somewhere that she missed her station, where she had
> to get down. The poem starts as
>
> "She sits within a subway car (start of the poem)
> Her fancy lighted by a star
> ......
> ......
> ......
> ......
> And journeys a mile beyond her station" (end of the poem)
>
> This much I remember in that poem. Neither I know the poem's heading
> nor the poet's name.
>
> Can anyone of u get me the full text of this poem..I like it very much!!!!


When you're alone and life is making you lonely
You can always go - downtown.
When you've got worries all the noise and the hurry
Seems to help
I know - downtown.
Just listen to the music of the traffic in the city
Linger on the sidewalk where the neon signs are pretty
How can you lose?
The lights are much brighter there
you can forget all your troubles
Forget all your cares
so go - downtown
Things will be great when you're - downtown
No finer place for sure - downtown
Everything's waiting for you - downtown.

http://en.wikipedia.org/wiki/Daffodil#cite_note-DaffsNA-1
http://en.wikipedia.org/wiki/Narcissus_(mythology)
The Narcissus flower is named after Narcissus. This was after he supposedly turned into a flower when he died, by looking at himself in the water too long. This forced him to stay there, because he was the god of beauty and he could only fall in love with himself; he later died of despair as he could not grasp the 'stranger' in the water. [2] [3]







http://en.wikipedia.org/wiki/Daffodil
Narcissus is the botanic name for a genus of mainly hardy, mostly spring-flowering, bulbs in the Amaryllis family native to Europe, North Africa, and Asia. There are also several Narcissus species that bloom in the autumn.
http://en.wikipedia.org/w/index.php?title=Daffodil&redirect=no
Daffodil is a common English name, sometimes used now for all varieties, and is the chief common name of horticultural prevalence used by the American Daffodil Society
Scientific classification
Kingdom: Plantae

Division: Magnoliophyta

Class: Liliopsida

Order: Asparagales

Family: Amaryllidaceae

Genus: Narcissus
L